Dr. Bill Cortner is driving to his lab with Jan Compton, his fiancée, when a terrible car crash leaves her decapitated. Cortner, however, is undaunted by what would seem an impossible setback. A transplant specialist, he is thrilled at the chance to carry out the first ever head transplant. With Compton's head kept alive in his lab, Cortner prepares for the pioneering but unconventional operation. Before anything else, though, he must find a body.